Givaudan Active Beauty launches Masknyl™ to relieve skin issues associated with mask-wearing

Microbiome-activated express skin perfector crafted by white biotech to let skin breathe

28 Sep 2021 · 09:00 CEST

Givaudan Active Beauty presents Masknyl™, an active ingredient able to counteract redness, inflammation and hyperpigmentation due to mask-wearing. Crafted by white biotechnology and activated by the skin microflora, this phytoactive ingredient has been designed thanks to our biocatalysis and microbiomics expertise to reveal its efficacy in only 24 hours¹. 

People wearing masks

Relief for ‘maskne’ and related skin issues

Skin discomfort and sensitivity experienced by consumers around the world have been aggravated by the use of face masks during the COVID-19 pandemic. The warm, humid environment created by breathing inside a face mask creates the ideal microclimate for excessive bacterial growth, quickly generating pore obstructions and pimples. This is exacerbated by the constant rubbing of the mask and its straps, further inflicting redness and irritation.

Familiar to 74%² of consumers worldwide, the term 'maskne' refers not just to breakouts but a range of skin issues due to mask-wearing such as sensitivity, redness and inflammation. With more than 60%¹ of the population continuing to wear face masks for public transportation and indoor activities, consumers will need to take care of their skin more than ever before.

“Masknyl™ is a phytoactive ingredient crafted from sophorin (phytomelin), a flavonoid with well-documented benefits in terms of antioxidant action, soothing and wound-healing. Already used in the cosmetic industry at limited dosage due to its poor solubility, biotechnology has enabled us to improve the bioavailability of sophorin (phytomelin) through glycosylation to craft Masknyl™. This new China compliant molecule is activated by the skin microflora and improves solubility by a factor of 14,000, offering rapid efficacy in terms of soothing and anti-redness activity.”

Mathias Fleury, Category Manager Active Beauty

Significant results in only 24 hours

Following activation by the skin microbiome, Masknyl™ offers triple action on the skin at a biological level. Clinical tests on volunteers wearing masks demonstrated that the phytoactive is able to:

  • Visibly reduce red spots and heal skin inflammation in just 24 hours (in particular where a surgical mask has been worn), by -34.2% versus placebo
  • Control and reduce hyperpigmentation and brown spots in just four days (-3.5% versus placebo)
  • Improve skin comfort and texture, with 74% of panellists highlighting the fact that their skin was softer and less tight

Smart solution for cosmetic efficacy

Givaudan's Active Beauty team has now crafted Mask Tonic, powered by Masknyl™ to prevent all kinds of skin discomfort due to mask-wearing. Suitable for all skin types and family members (from 3 years old), even the most sensitive, our 92% natural-origin genderless day cream reduces redness and controls hyperpigmentation. Thanks to PrimalHyal™ 300 and Unitamuron™ H-22 Green, it protects, repairs and increases elasticity. Application of this light emulsion provides a delicate sensation of freshness, leaving skin perfectly hydrated even when covered.

  1. Proved by clinical test on volunteers wearing masks
  2. Masknyl™ Global CMI Study, Givaudan Active Beauty, September 2021

About Givaudan
Givaudan is the global leader in the creation of flavours and fragrances, with its heritage stretching back over 250 years, the Company has a long history of innovating tastes and scents. From a favourite drink to your daily meal, from prestige perfumes to cosmetics and laundry care, its creations inspire emotions and delight millions of consumers the world over. The Company is committed to driving purpose-led, long-term growth while leading the way to improve happiness and health for people and nature. In the fiscal year 2020, the Company employed almost 16,000 people worldwide and achieved sales of CHF 6.3 billion and a free cash flow of 12.8% of sales. Let’s imagine together on

About Givaudan Fragrance & Beauty
Driven by passion and innovation, Givaudan Fragrance & Beauty aims to bring delightful and memorable sensorial experiences to consumers around the world. Currently present in all major markets, we strive to be the creative partner of choice for customers not only in personal, fabric, hygiene and home care but also in fine fragrances and beauty overall. As the global leader in fragrance creation, the Company is committed to creating fragrances and beauty products for happier, healthier lives with love for nature. Our customers benefit from our expertise in three business units: Fine Fragrances, Consumer Products, and Fragrance Ingredients and Cosmetics Ingredients. We invite you to ‘engage your senses’ and learn more at

About Givaudan Active Beauty
Givaudan Active Beauty offers an extensive portfolio of innovative active cosmetic ingredients designed to bring beauty to the world. Inspired by the beauty needs of consumers worldwide, Active Beauty offers award-winning products for an expanded range of benefits including anti-ageing, self-tanning, soothing, hydrating, cooling, and more. Our cutting-edge technologies draw on science and nature to create high-performing molecules and functional agents, including customised carrier systems. Part of Givaudan Fragrance & Beauty, Active Beauty leads the market in crafting innovative products supported by our strong expertise in advanced and applied sciences. We invite you to ‘engage your senses’ and learn more about Active Beauty at

For further information please contact
Pauline Martin, Operational Marketing & Communications Manager
T +33 3 2688 8417